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The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
1110003G10Rik; AC19; DNA-directed RNA polymerase I 16 kDa polypeptide; DNA-directed RNA polymerase I subunit D; DNA-directed RNA polymerases I and III subunit RPAC2; hRPA19; POLR1C; Polr1d; polymerase (RNA) I polypeptide D; polymerase (RNA) I polypeptide D, 16kDa; polymerase (RNA) I subunit D; Protein POLR1D, isoform 2; RNA polymerase 1-3; RNA polymerase I 16 kDa subunit; RNA polymerase I subunit D; RNA polymerases I and III subunit AC2; RPA16; RPA9; RPAC2; RPC16; Rpo1-3; TCS2
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