PPP1R3A, the glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. PPP1R3A encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.
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glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle; glycogen-associated regulatory subunit of protein phosphatase-1; GM; PP1G; PPP1R3; protein phosphatase 1; protein phosphatase 1 glycogen- associated regulatory subunit; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase 1 regulatory subunit 3A; protein phosphatase 1 regulatory subunit GM; protein phosphatase 1, regulatory (inhibitor) subunit 3A; protein phosphatase 1, regulatory subunit 3A; Protein phosphatase type-1 glycogen targeting subunit; regulatory subunit 3A; RG1; serine /threonine specific protein phosphatase; type-1 protein phosphatase skeletal muscle glycogen targeting subunit