This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
InvitrogenRUNX3 Monoclonal Antibody (R3-5G4), Biotin, eBioscience™ RUNX3 Monoclonal Antibody (R3-5G4), Biotin, eBioscience™
Cat # 13-9817-82
InvitrogenRUNX3 Monoclonal Antibody (R3-5G4), eFluor 660, eBioscience™ RUNX3 Monoclonal Antibody (R3-5G4), eFluor 660, eBioscience™
Cat # 50-9817-82
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