RunX proteins are thought to be involved in lineage specification of CD8 T cells. These proteins, especially RUNX3 can provide critical insight for understanding the mutually exclusive expression of coreceptors in mature thymocytes.
RUNX3 is believed to be a key regulator of CD8 T cell generation.
Acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; alpha 3 subunit; CBF-alpha 3; CBF-alpha-3; Core-binding factor; Core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; Oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; Polyomavirus enhancer-binding protein 2 alpha C; Polyomavirus enhancer-binding protein 2 alpha C subunit; Runt-related transcription factor 3; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; transcription factor AML2
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