Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
MGC119118; MGC119119; MGC119120; MGC119121; MGC134637; T2R49; T2R56; TAS2R49; Taste receptor type 2 member 20; Taste receptor type 2 member 49; Taste receptor type 2 member 56; taste receptor, type 2, member 20; taste receptor, type 2, member 49