Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with b catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.
5730422P05Rik; A1; AA408400; AGM8; ALF2; ASP-I2; AW209082; bHLHb19; BHLHB21; Class A helix-loop-helix transcription factor ME2; class B basic helix-loop-helix protein 19; Class B basic helix-loop-helix protein 21; E12; E12/E47; E2.2; E2-2; E2A; E47; FECD3; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF1; ITF-1; ITF2; ITF-2; ITF-2b; kappa-E2-binding factor; Me2; MITF-2; MITF-2A; MITF-2B; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan1; Pan2; PTHS; SEF2; SEF-2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; SL3-3 enhancer factor 2; Tcf3; TCF-3; TCF4; TCF-4; Tcfe2a; TFE; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor
25 µg
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist nowIf an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support