Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
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B lymphocyte gene 1; BCE-1; BCE1; E(spI); enhancer of split groucho 4; ESG4; Grg-4; GRG4; Groucho-related protein 4; homolog of Drosophila E(sp1); Protein BCE-1; transducin-like enhancer of split 4; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, homolog of Drosophila E(sp1); Transducin-like enhancer protein 4