RNA-binding protein involved in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Bruno-like protein 1; BRUNOL1; CAG repeat domain; CAG repeat protein 4; CAGH4; CELF-3; CELF3; CUG-BP and ETR-3 like factor 3; CUG-BP- and ETR-3-like factor 3; CUGBP Elav-like family member 3; ELAV-type RNA-binding protein 1; ERDA4; ETR-1; Expanded repeat domain protein CAG/CTG 4; expanded repeat domain, CAG/CTG 4; RNA-binding protein BRUNOL-1; TNRC4; trinucleotide repeat containing 4; Trinucleotide repeat-containing gene 4 protein