Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.
InvitrogenThemis Monoclonal Antibody (1TMYS), PE, eBioscience™ Themis Monoclonal Antibody (1TMYS), PE, eBioscience™
Cat # 12-5918-80
InvitrogenThemis Monoclonal Antibody (1TMYS), eFluor 660, eBioscience™ Themis Monoclonal Antibody (1TMYS), eFluor 660, eBioscience™
Cat # 50-5918-82
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