Subunit B (~57kDa) is a non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles. This polypeptide is associated with the cytoplasmic face of the vacuolar membrane when the V-ATPase complex is fully assembled.
H(+)-transporting V1 sector ATPase subunit B; V-ATPase 57 kDa subunit; V-ATPase subunit B; V-type proton ATPase subunit B; Vacuolar proton pump subunit B