This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
C20orf122; dJ211D12.4; protease inhibitor WAP2; Putative protease inhibitor WAP12; single WAP motif protein 2; SWAM2; WAP four-disulfide core domain protein 12; WAP2; Whey acidic protein 2