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A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
AMYB; A-myb; G1-419-6; MYB proto-oncogene like 1; MYBA; MYBL1; myb-like protein 1; Myb-related protein A; myeloblastosis oncogene-like 1; repro9; VMYB; v-myb avian myeloblastosis viral oncogene homolog-like 1
100 µL
100 µL
100 µg
100 µL
100 µL
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