|Tested species reactivity||Bovine, Chicken, Human, Mouse, Rat, Zebrafish|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||N-terminal fragment of human 14-3-3 gamma.|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: antigen standard for YWHAG (transient overexpression lysate), Hela whole cell extract.
14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a protein's function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.