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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||N-terminal fragment of human 14-3-3 gamma where the N-terminal Val was acetylated.|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Suggested positive control: antigen standard for YWHAG (transient overexpression lysate), HeLa whole cell extract.
14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a proteinâ€™s function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Identification and validation of platelet low biological variation proteins, superior to GAPDH, actin and tubulin, as tools in clinical proteomics.
MA1-16587 was used in western blot to study the platelet proteome to identify proteins with low variability suitable for use as quantitation controls in clinical proteomic investigations
|Baumgartner R,Umlauf E,Veitinger M,Guterres S,Rappold E,Babeluk R,Mitulović G,Oehler R,Zellner M||Journal of proteomics (94:540)||2013|
14-3-3 gamma; KCIP-1; protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
14-3-3GAMMA; PPP1R170; YWHAG