Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MDAPKAGYA FEYLIETLND SSHKKFFDVS KLGTKYDVLP YSIRVLLEAA VRNCDGFLMK KEDVMNILDW KTKQSNVEVP FFPARVLLQD FTGIPAMVDF AAMREAVKTL GGDPEKVHPA CPTDLTVDHS LQIDFSKCAI QNAPNPGGGD LQKAGKLSPL KVQPKKLPCR GQTTCRGSCD SGELGRNSGT FSSQIENTPI LCPFHLQPVP EPETVLKNQE VEFGRNRERL QFFKWSSRVF KNVAVIPPGT GMAHQINLEY LSRVVFEEKD LLFPDSVVGT DSHITMVNGL GILGWGVGGI ETEAVMLGLP VSLTLPEVVG CELTGSSNPF VTSIDVVLGI TKVS (1-343 aa encoded by BC017880)
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ23381; IRE-BP 2; Iron regulatory protein 2; iron-responsive element binding protein 2; Iron-responsive element-binding protein 2; IRP2
Gene Aliases: IREB2; Irp2
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