This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Matrix metallopeptidase 16 during embryonic development, reproduction, and tissue remodeling. MMP-16 is also involved in the ECM degradation processes associated with arthritis and metastasis. In humans, MMP-16 is a part of a cluster of MMP genes at the 11q22.3 locus.
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Protein Aliases: C8orf57; matrix metallopeptidase 16 (membrane-inserted); Matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP-16; MMP-X2; MT-MMP 3; MT-MMP2; MT-MMP3; MT3-MMP; MT3MMP; MTMMP3; Putative transmembrane protein C8orf57
Gene Aliases: C8orf57; MMP-X2; MMP16; MMPX2; MT-MMP2; MT-MMP3; MT3-MMP
UniProt ID: (Human) P51512
Entrez Gene ID: (Human) 4325