The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Horse, Guinea pig_10141, Pig, Orangutan, Monkey, Gorilla and Chimpanzee
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAG repeat protein 32; CAGH32; Domino homolog; E1A-binding protein p400; hDomino; mDomino; P400; p400 kDa SWI2/SNF2-related protein; p400 SWI2/SNF2-related protein; TNRC12; trinucleotide repeat containing 12; Trinucleotide repeat-containing gene 12 protein
Gene Aliases: 1700020J09Rik; AU023439; CAGH32; EP400; KIAA1498; KIAA1818; mDomino; mKIAA1498; P400; TNRC12