Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAAFSKYLT ARNSSLAGAA FLLLCLLHKR RRALGLHGKK SGKPPLQNNE KEGKKERAVV DKVFFSRLIQ ILKIMVPRTF CKETGYLVLI AVMLVSRTYC DVWMIQNGTL IESGIIGRSR KDFKR (1-124 aa encoded by BC068509)
Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum" disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 70 kDa peroxisomal membrane protein; ATP-binding cassette sub-family D member 3; ATP-binding cassette, sub-family D (ALD), member 3; dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); peroxisomal membrane protein 1 (70kD, Zellweger syndrome); Peroxisomal membrane protein-1 (70kD); PMP70
Gene Aliases: ABC43; ABCD3; CBAS5; PMP70; PXMP1; ZWS2
UniProt ID: (Human) P28288
Entrez Gene ID: (Human) 5825
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