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|Tested species reactivity||Human|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the cytoplasmic domain of human amiloride sensitive cation channel 3|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ACCN3; acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid-sensing (proton-gated) ion channel 3; amiloride-sensitive cation channel 3, testis; hASIC3; hTNaC1; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; SLNAC1; testis sodium channel 1; TNAC1
ACCN3; ASIC3; DRASIC; SLNAC1; TNAC1