|Tested species reactivity||Cat, Hamster, Human, Non-human primate, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human lung Angiotensin Converting Enzyme.|
|Storage buffer||tissue culture supernatant diluted in PBS|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Neat-1:10 (10 µl for 10^6 cells in 100 µl)|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25293 detects Angiotensin Converting Enzyme from human, rat, feline, hamster, and monkey samples.
MA1-25293 has been successfully used in immunoprecipitation procedures.
The MA1-25293 immunogen is human lung Angiotensin Converting Enzyme.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.