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      The product (cat # PA5-29864) that you're looking for has been discontinued. Please contact Technical Support Technical Support with any questions.

      Invitrogen™

      ADAMTS1 Antibody

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      Catalog #:PA5-29864

       

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      Product Details

      TESTED APPLICATIONS DILUTION
      Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
      Western Blot (WB) 1:500-1:3000
      Tested Species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Recombinant fragment corresponding to a region within amino acids 318 and 643 of Human ADAMTS1
      Form Liquid
      Concentration 0.99 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer PBS, pH 7, with 1% BSA, 20% glycerol
      Contains 0.01% thimerosal
      Storage conditions -20° C, Avoid Freeze/Thaw Cycles

      Product Specific Information

      PA5-29864 targets ADAMTS1 in IHC (P) and WB applications and shows reactivity with Human samples.

      The PA5-29864 immunogen is recombinant fragment corresponding to a region within amino acids 318 and 643 of Human ADAMTS1.

      Background/Target Information

      This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Bioinformatics

      Protein Aliases: 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; METH-1; METH1

      Gene Aliases: C3-C5; METH1

      UniProt ID: (Human) Q9UHI8

      Entrez Gene ID: (Human) 9510

      Molecular Function: Signaling molecule Protease Metalloprotease

      Suggested Secondary Antibodies

      Documents

      Material safety data sheets (MSDS)

      Performance Guarantee

      If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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