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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100 | - |
Flow Cytometry (Flow) |
1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1G9 |
Immunogen |
Recombinant protein within human ADAMTS13 aa 150-350. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Storage conditions |
-20°C |
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 13; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 13; ADAM-TS 13; ADAMs; metalloendopeptidases; von Willebrand factor-cleaving protease; vWF-cleaving protease; vWF-CP
Gene Aliases: ADAMTS13; C9orf8; UNQ6102/PRO20085
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