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Product Details
H00000127-M03A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1D2
Immunogen
ADH4 (NP_000661, 52 a.a. approximately 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Sequence of this protein is as follows: SVIDSKFEGL AFPVIVGHEA AGIVESIGPG VTNVKPGDKV IPLYAPLCRK CKFCLSPLTN LCGKISNLKS PASDQQLMED KTSRFTCKGK PVYHFFGTS
Target Information
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alcohol dehydrogenase 4; Alcohol dehydrogenase class II pi chain; aldehyde reductase; All-trans-retinol dehydrogenase [NAD(+)] ADH4; epididymis secretory protein Li 4
Gene Aliases: ADH-2; ADH4; HEL-S-4
UniProt ID: (Human) P08319
Entrez Gene ID: (Human) 127
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
NADPH:quinone reductase activity
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase activity, zinc-dependent
alditol:NADP+ 1-oxidoreductase activity
retinol dehydrogenase activity
all-trans retinal binding
zinc ion binding
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
benzaldehyde dehydrogenase activity
retinol binding
ethanol binding
NAD binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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