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Product Details
H00023394-M01A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6B8
Immunogen
ADNP (NP_056154, 1018 a.a. approximately 1102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: TMQGDREQLK WKNSSYGKVE GFWSKDQSQW KNASENDERL SNPQIEWQNS TIDSEDGEQF DNMTDGVAEP MHGSLAGVKL SSQQA
Target Information
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activity-dependent neuroprotective protein; activity-dependent neuroprotector; Activity-dependent neuroprotector homeobox protein; ADNP homeobox 1
Gene Aliases: ADNP; ADNP1; HVDAS; KIAA0784; MRD28
UniProt ID: (Human) Q9H2P0
Entrez Gene ID: (Human) 23394
transcription, DNA-templated
regulation of transcription, DNA-templated
short-term memory
response to carbohydrate
response to inorganic substance
negative regulation of gene expression
regulation of protein ADP-ribosylation
positive regulation of cGMP biosynthetic process
cellular response to extracellular stimulus
negative regulation of protein binding
activation of protein kinase activity
nitric oxide homeostasis
negative regulation of neuron apoptotic process
estrous cycle
positive regulation of axon extension
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of synaptic transmission
positive regulation of synapse assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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