|Tested species reactivity||Fish, Human, Mouse, Rat, Xenopus, Zebrafish|
|Host / Isotype||Sheep / IgG|
|Immunogen||synthetic peptide ERVNEAREELMRMLA, corresponding to amino acids 98-112 of Human ADP Ribosylation Factor.|
|Storage buffer||tris glycine with 1mM EDTA, 30% EACA, 0.01% benzamidine|
|Contains||0.01% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-28093 detects ADP ribosylation factor from human, mouse samples.
PA1-28093 has been successfully used in Western blot applications.
The PA1-28093 immunogen is: Synthetic peptide: ERVNEAREELMRMLA, corresponding to amino acids 98-112 of Human ADP Ribosylation Factor.
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.