MA3-081 detects AID from human, and mouse samples.
MA3-081 has been successfully used in Western blot, immunofluorescence, flow cytometry, and ELISA applications.
The MA3-081 immunogen is the synthetic peptide coupled to ovalalbumin, aa 185 to 198. MA3-081 detects Isoform 1 (~24kDa) and Isoform 2 (~22kDa) in human samples.
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activation induced deaminase; Activation-induced cytidine deaminase; AID; ARP2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase
Gene Aliases: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2