NeoBiotechnologies

AIF1/Iba1 Recombinant Mouse Monoclonal Antibody (rAIF1, 1909)

View all (37) IBA1 antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Product Image Gallery

AIF1/Iba1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human tonsil using AIF1, Iba1 Recombinant Monoclonal Antibody (Product # 199-MSM2-P1ABX).

AIF1/Iba1 Antibody in Peptide array (ARRAY) — Analysis of Protein Array containing more than 19,000 full-length human proteins AIF1, Iba1 Recombinant Monoclonal Antibody (Product # 199-MSM2-P1ABX). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

AIF1/Iba1 Antibody — SDS-PAGE Analyis Purified AIF1, Iba1 Recombinant Monoclonal Antibody (Product # 199-MSM2-P1ABX). Confirmation of Purity and Integrity of Antibody.

Product Details

199-MSM2-P1ABX

Applications	Tested Dilution	Publications
Immunohistochemistry (Paraffin) (IHC (P))	1-2 µg/mL	-
Peptide Array (Array)	Assay-dependent	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Mouse / IgG1, kappa
Class	Recombinant Monoclonal
Type	Antibody
Clone	rAIF1, 1909
Immunogen	Purified recombinant human AIF1 protein (around aa 1-146) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein G
Storage buffer	PBS, pH 7.4
Contains	no preservative
Storage conditions	-20°C or -80°C if preferred

Product Specific Information

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

Target Information

AIF1 is induced by cytokines and interferon. It is thought to be involved in the negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: AIF-1; Allograft inflammatory factor 1; DADB-70P7.8; DASS-82G15.2; Em:AF129756.17; Iba; interferon gamma responsive transcript; Ionized calcium-binding adapter molecule 1; Protein G1

Gene Aliases: AIF-1; AIF1; G1; IBA1; IRT-1; IRT1

UniProt ID: (Human) P55008

Entrez Gene ID: (Human) 199

Molecular Function: calmodulin-related

Function(s)

microglial cell activation positive regulation of protein phosphorylation phagocytosis, engulfment inflammatory response negative regulation of gene expression positive regulation of muscle hyperplasia Rac protein signal transduction actin filament polymerization cellular response to extracellular stimulus cellular response to hormone stimulus positive regulation of T cell proliferation negative regulation of apoptotic process positive regulation of nitric oxide biosynthetic process positive regulation of smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation response to axon injury actin filament bundle assembly response to glucocorticoid response to electrical stimulus cellular response to morphine cellular response to interferon-gamma cellular response to hydroperoxide negative regulation of smooth muscle cell chemotaxis positive regulation of smooth muscle cell chemotaxis positive regulation of monocyte chemotaxis ruffle assembly positive regulation of G1/S transition of mitotic cell cycle positive regulation of T cell migration

Process(es)

molecular_function calcium ion binding actin filament binding

AIF1/Iba1 Recombinant Mouse Monoclonal Antibody (rAIF1, 1909)

Product Details

199-MSM2-P1ABX

Immunohistochemistry (Paraffin) (IHC (P))

Peptide Array (Array)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!