Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.
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Protein Aliases: Adenylate kinase 2, mitochondrial; Adenylate kinase isoenzyme 2; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; AK 2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; testis secretory sperm-binding protein Li 220n
Gene Aliases: ADK2; AK2
UniProt ID: (Human) P54819
Entrez Gene ID: (Human) 204