For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
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Protein Aliases: Adenylate kinase 3; Adenylate kinase 3 alpha-like 1; adenylate kinase 6, adenylate kinase 3 like 1; AK 3; AK3; AK4; GTP:AMP phosphotransferase AK3, mitochondrial; GTP:AMP phosphotransferase, mitochondrial
Gene Aliases: AK3; AK3L1; AK6; AKL3L; AKL3L1; FIX
UniProt ID: (Human) Q9UIJ7
Entrez Gene ID: (Human) 50808
Molecular Function: nucleotide kinase