For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
This gene encodes a member of the A-kinase anchoring protein family, a group of functionally related proteins that bind to a regulatory subunit of cAMP-dependent protein kinase A and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
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Protein Aliases: A kinase (PRKA) anchor protein 7; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoform gamma; A-kinase anchor protein 7 isoforms alpha and beta; A-kinase anchor protein 9 kDa; AKAP 18; AKAP-7 isoform gamma; AKAP-7 isoforms alpha and beta; PRKA7 isoform gamma; PRKA7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoforms alpha/beta
Gene Aliases: AKAP15; AKAP18; AKAP7
UniProt ID: (Human) O43687
Entrez Gene ID: (Human) 9465