PA5-30773 targets AKR1B10 in IF and WB applications and shows reactivity with Human samples.
The PA5-30773 immunogen is recombinant fragment corresponding to a region within amino acids 120 and 316 of Human AKR1B10.
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
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Protein Aliases: AKR1B11; AKR1B12; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B10; aldo-keto reductase family 1, member B10 (aldose reductase); aldo-keto reductase family 1, member B11 (aldose reductase-like); Aldose reductase-like; aldose reductase-like 1; aldose reductase-like peptide; Aldose reductase-related protein; ALDRLn; ARL-1; ARL1; ARP; hARP; HIS; HSI; member B11 (aldose reductase-like); SI reductase; Small intestine reductase
Gene Aliases: AKR1B10; AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI
UniProt ID: (Human) O60218
Entrez Gene ID: (Human) 57016