Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
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Protein Aliases: 17-alpha-HSD; 17-alpha-hydroxysteroid dehydrogenase; 2-dihydrobenzene-1; 2-diol dehydrogenase; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-alpha-HSD; 20-alpha-hydroxysteroid dehydrogenase; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD3; 3-alpha-hydroxysteroid dehydrogenase; aldo-keto reductase C; Aldo-keto reductase family 1 member C1; Aldo-keto reductase family 1 member C2; Aldo-keto reductase family 1 member C21; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C21; aldo-keto reductase family 1, member C6; Chlordecone reductase homolog HAKRC; Chlordecone reductase homolog HAKRD; DD-2; DD/BABP; DD1/DD2; DD2; dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase 2; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III; dihydrodiol dehydrogenase isoform DD1; Dihydrodiol dehydrogenase/bile acid-binding protein; HBAB; hepatic dihydrodiol dehydrogenase; High-affinity hepatic bile acid-binding protein; Indanol dehydrogenase; pseudo-chlordecone reductase; testicular 17,20-desmolase deficiency; Trans-1; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase; type II dihydrodiol dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase
Gene Aliases: 2-ALPHA-HSD; 20-ALPHA-HSD; AKR1C-pseudo; AKR1C1; AKR1C2; Akr1c21; Akr1c6; BABP; C9; DD; DD-2; DD/BABP; DD1; DD1/DD2; DD2; DDH; DDH1; DDH2; H-37; HAKRC; HAKRD; HBAB; Hsd17b5; MBAB; MCDR2; SRXY8; TDD