Suggested positive control: HeLa, antigen standard for AKT2 (transient overexpression lysate).
Akt, protein kinase B (PKB), is a serine/threonine kinase, which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
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Protein Aliases: AKT3; murine thymoma viral (v-akt) homolog-2; PKB beta; PKB gamma; PKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B beta; Protein kinase B gamma; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC-beta serine/threonine-protein kinase; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-beta; RAC-PK-gamma; STK-2; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Gene Aliases: AKT2; AKT3; HIHGHH; MPPH; MPPH2; PKB-GAMMA; PKBB; PKBBETA; PKBG; PRKBB; PRKBG; RAC-BETA; RAC-gamma; RAC-PK-gamma; STK-2
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase