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Product Details
TA502841
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4E8
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-100 and 413-512 of human ALDH1A3 produced in E.coli.
Conjugate
Unconjugated
Form
liquid
Concentration
0.8 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Target Information
ALDH1A3 are aldehyde dehydrogenase isozymes which are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by the ALDH1A3 gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetaldehyde dehydrogenase 6; aldehyde dehydrogenase 1 family, member A3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDHA1A3; RALDH-3; Retinaldehyde dehydrogenase 3
Gene Aliases: ALDH1A3; ALDH1A6; ALDH6; MCOP8; RALDH3
UniProt ID: (Human) P47895
Entrez Gene ID: (Human) 220
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
optic cup morphogenesis involved in camera-type eye development
retinoic acid biosynthetic process
locomotory behavior
nucleus accumbens development
inner ear morphogenesis
retinol metabolic process
retinoic acid metabolic process
retinal metabolic process
positive regulation of apoptotic process
embryonic eye morphogenesis
neuromuscular process controlling balance
oxidation-reduction process
righting reflex
olfactory pit development
face development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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