MA5-14576 targets Alpha methylacyl-CoA-racemase in WB, IF and IHC (P) applications and shows reactivity with Human samples.
The MA5-14576 immunogen is human p504s/AMACR polypeptide.
P504S/AMACR/a-Methylacyl-CoA Racemase is an essential enzyme in the b-oxidation of branched-chain fatty acids. High expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue. The expression of P504S is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
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Protein Aliases: 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; amcr; OTTHUMP00000219978; OTTHUMP00000219979
Gene Aliases: AMACR; AMACRD; CBAS4; RACE; RM
UniProt ID: (Human) Q9UHK6
Entrez Gene ID: (Human) 23600