MA5-15360 targets AMACR in IF, IHC, and WB applications and shows reactivity with Human and mouse samples.
The MA5-15360 immunogen is purified recombinant fragment of human AMACR expressed in E. Coli.
MA5-15360 detects AMACR which has a predicted molecular weight of approximately 42kDa.
P504S/AMACR/a-Methylacyl-CoA Racemase is an essential enzyme in the b-oxidation of branched-chain fatty acids. High expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue. The expression of P504S is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
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Protein Aliases: 2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; alpha-methylacyl-Coenzyme A racemase; AMACR
Gene Aliases: AMACR; AMACRD; CBAS4; Macr1; RACE; RM