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Product Details
H00000265-M04
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
6G3
Immunogen
AMELX (NP_001133, 93 a.a. approximately 191 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: PVIPQQPMMP VPGQHSMTPI QHHQPNLPPP AQQPYQPQPV QPQPHQPMQP QPPVHPMQPL PPQPPLPPMF PMQPLPPMLP DLTLEAWPST DKTKREEVD
Target Information
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); Amelogenin, X isoform
Gene Aliases: AI1E; AIH1; ALGN; AMELX; AMG; AMGL; AMGX
UniProt ID: (Human) Q99217
Entrez Gene ID: (Human) 265
osteoblast differentiation
epithelial to mesenchymal transition
chondrocyte differentiation
cell adhesion
signal transduction
cell proliferation
biomineral tissue development
positive regulation of collagen biosynthetic process
tooth mineralization
odontogenesis of dentin-containing tooth
ion homeostasis
enamel mineralization
positive regulation of tooth mineralization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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