Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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1 µg/mL of MA5-45622 was sufficient for detection of AMIGO-1 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |Detects approximately 60-80kDa depending on maturity/glycosylation.
This antibody was formerly sold as clone S86-36.
Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adhesion molecule with Ig-like domain 1; alivin 2; Alivin-2; AMIGO 1; AMIGO-1; AMIGO1; amigo1 {ECO:0000250|UniProtKB:Q80ZD8}; amphoretin-induced gene and ORF; amphoterin induced gene and ORF (Amigo); amphoterin-induced gene and ORF; Amphoterin-induced protein 1; MGC25558; OTTHUMP00000013379; RP23 89M15.6; transmembrane protein AMIGO
Gene Aliases: ALI2; AMIGO; AMIGO-1; AMIGO1; KIAA1163
UniProt ID: (Human) Q86WK6, (Mouse) Q80ZD8, (Rat) Q80ZD7
Entrez Gene ID: (Human) 57463, (Mouse) 229715, (Rat) 295365
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