This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 425O18-1; angiopoietin-like 4; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; ANGPTL4 C-terminal chain; ANGPTL4 N-terminal chain; ARP4; Fasting-induced adipose factor; FIAF; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; NL2; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PGAR; pp1158; PPARG angiopoietin related protein; Secreted protein Bk89
Gene Aliases: ANGPTL4; ARP4; Bk89; Farp; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; PP1158; PSEC0166; TGQTL; UNQ171; UNQ171/PRO197
Molecular Function: signaling molecule