This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: IQQSLLESSR SQELSGPASN GGISQTNTYD AQYERAIQES LLTSTEGLCP SALSETSRFD NDLQLAMELS AKELEEWELR LQEE
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 79%.
ANKRD13A, also named as ANKRD13, a 590 amino acid protein, which contains two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. ANKRD13A localizes in the cell membrane. ANKRD13A as ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin, not bind 'Lys-48'-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.