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Product Details
75-418-FL550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N429/19
Immunogen
Fusion protein amino acids 1-294 (cytoplasmic N-terminus) of human ANO6 (accession number Q4KMQ2) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
550/575 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
May act as a calcium-activated chloride channel.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F
Gene Aliases: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F
UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9
Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated ion channel activity
voltage-gated chloride channel activity
protein binding
phospholipid scramblase activity
protein homodimerization activity
molecular_function
chloride channel activity
dendritic cell chemotaxis
activation of blood coagulation via clotting cascade
cation transport
chloride transport
blood coagulation
phospholipid transport
phospholipid scrambling
bone mineralization involved in bone maturation
regulation of anion transport
calcium activated phospholipid scrambling
calcium activated phosphatidylserine scrambling
calcium activated phosphatidylcholine scrambling
calcium activated galactosylceramide scrambling
phosphatidylserine exposure on apoptotic cell surface
phosphatidylserine exposure on blood platelet
cation transmembrane transport
positive regulation of potassium ion export
chloride transmembrane transport
positive regulation of endothelial cell apoptotic process
lipid transport
positive regulation of bone mineralization
bleb assembly
ion transmembrane transport
positive regulation of ion transmembrane transport
purinergic nucleotide receptor signaling pathway
sodium ion transmembrane transport
positive regulation of apoptotic process
negative regulation of cell volume
pore complex assembly
positive regulation of phagocytosis, engulfment
calcium ion transmembrane transport
positive regulation of monocyte chemotaxis
regulation of anion transmembrane transport
transport
ion transport
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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