This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
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Protein Aliases: 35-alpha calcimedin; Annexin 3; Annexin A3; Annexin III; Annexin III (lipocortin III); annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha); Annexin-3; Annexin3; ANXA 3; calcimedin 35-alpha; Inositol 1,2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; PAP-III; Placental anticoagulant protein III
Gene Aliases: ANX3; ANXA3
UniProt ID: (Human) P12429
Entrez Gene ID: (Human) 306