|ELISA (ELISA)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||C-terminal peptide of AP-2 alpha (PNSHTDNNAKSSDKEEKHRK).|
|Storage buffer||PBS, pH 7.4|
|Contains||0.09% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-90265 detects AP2 alpha + beta from human samples.
MA1-90265 has been successfully used in immunohistochemistry (frozen and paraffin tissue), ELISA, Western blot applications.
The MA1-90265 immunogen is: C-terminal peptide of AP-2 alpha (PNSHTDNNAKSSDKEEKHRK).
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activating enhancer binding protein 2 beta; Activating enhancer-binding protein 2-alpha; Activating enhancer-binding protein 2-beta; Activator protein 2; AP-2; AP-2 transcription factor; AP-2alpha; AP2-alpha; AP2-beta; AP2TF; BOFS; FLJ51761; TFAP2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2 beta (activating enhancer binding protein 2 beta); Transcription factor AP-2-alpha; Transcription factor AP-2-beta
Gene Aliases: AP-2; AP-2alpha; AP-2B; AP2-B; AP2TF; BOFS; TFAP2; TFAP2A; TFAP2B
Molecular Function: transcription factor
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