MA1-872 detects AP-2 from human, mouse, and chicken samples.
MA1-872 has been successfully used in Western blot, immunoprecipitation, and immunofluorescence applications. By Western blot, this antibody detects a 45-50 kDa band representing AP-2. For Western blotting, block with BSA only (not milk).
The MA1-872 immunogen is the N-terminus of human AP2a.
AP-2, also known as ERF-1, plays an important role in regulating estrogen receptor expression. It also may play a role in the development of ectodermal-derived tissue. Mutations in the AP-2 gene have been linked to many eye chamber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activating enhancer-binding protein 2 alpha; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2; AP-2 transcription factor; AP2-alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); Transcription factor AP-2-alpha
Gene Aliases: AP-2; Ap-2 (a); AP-2alpha; Ap2; AP2alpha; AP2TF; BOFS; Tcfap2a; TFAP2; TFAP2A
Molecular Function: transcription factor