|Tested species reactivity||Rat, Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Recombinant N-terminal fragment of APC.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.05M sodium phosphate with 0.2% gelatin|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||4-6 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||4-6 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
MA1-25884 detects APC from human, mouse, and rat samples.
MA1-25884 has been successfully used in immunohistochemistry (paraffin), immunofluorescence, and immunocytochemsitry procedures.
The MA1-25884 immunogen is recombinant N-terminal fragment of APC.
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils.
MA1-25884 was used in ELISA and immunocytochemistry to investigate the interaction between BAP31 and CD11b/CD18
|Zen K,Utech M,Liu Y,Soto I,Nusrat A,Parkos CA||The Journal of biological chemistry (279:44924)||2004|