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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human APC with C-terminal fusion to MBP (maltose binding protein).|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-26195 detects APC from human and mouse samples.
MA1-26195 has been successfully used in immunoprecipitation, immunohistochemistry (frozen), immunofluorescence and Western blot procedures.
The MA1-26195 immunogen is human APC with C-terminal fusion to MBP (maltose binding protein).
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adenomatosis polyposis coli tumor suppressor; Adenomatous Polyposis Coli; Adenomatous polyposis coli protein; APC; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FPC; multiple intestinal neoplasia; Protein APC; protein phosphatase 1, regulatory subunit 46; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
AI047805; APC; AU020952; AW124434; BTPS2; CC1; DP2; DP2.5; DP3; GS; mAPC; Min; PPP1R46