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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Non-human primate, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from the internal region of the human Apg12 protein. This sequence differs from the mouse sequence by one amino acid.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.||Sarkar S,Davies JE,Huang Z,Tunnacliffe A,Rubinsztein DC||The Journal of biological chemistry (282:5641)||2007|
APG12; Apg12 (autophagy; Apg12 (autophagy, yeast) homolog; APG12L; ATG12 autophagy related 12 homolog; autophagy-related 12; autophagy-related protein 12; FBR93; HAPG12; ubiquitin-like protein ATG12; yeast) homolog
4931423H11Rik; A330058M13Rik; APG12; APG12L; ATG12; Atg12l; FBR93; HAPG12