Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: MSATWCSPEG QGMGQGPGRE VGGNSAASGP ASPIRDPCLS EAGLKGPPSA HPRRLCLLHR LVCFSGGLTS IQLSPRTCCS HQWAQLFSPA CFPQWRAPGC SLDDSRSLTR IRPVHLPGPS LD
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AGTRL1 ligand; Apelin; APJ endogenous ligand
Gene Aliases: APEL; APLN; XNPEP2
UniProt ID: (Human) Q9ULZ1
Entrez Gene ID: (Human) 8862
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