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Product Details
CF507094
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1E3
Immunogen
Full length human recombinant protein of human APOA5 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo-AV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; Apolipoprotein A5; apolipoprotein AV; FLJ97995; MGC126836; MGC126838; Regeneration-associated protein 3
Gene Aliases: APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788
Entrez Gene ID: (Human) 116519
phospholipid binding
enzyme activator activity
heparin binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
lipase binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
apolipoprotein
triglyceride metabolic process
cholesterol biosynthetic process
lipid transport
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process
regulation of intestinal cholesterol absorption
neuron projection regeneration
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
high-density lipoprotein particle assembly
lipoprotein metabolic process
tissue regeneration
cholesterol homeostasis
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of receptor-mediated endocytosis
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
triglyceride homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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