ApoE4 is one of the three major isoforms of ApoE (Apolipoprotein E). These three major isoforms (ApoE2, ApoE3, and ApoE4) correspond to three common ApoE alleles and are recognized according to their relative position after isoelectric focusing. Individuals carrying the common ApoE4 variant are at higher risk of coronary artery disease. ApoE4 is also the largest known genetic risk factor for late-onset Alzheimer's Disease (AD).
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Protein Aliases: AD2; Apo-E; Apolipoprotein E; apolipoprotein E3; LDLCQ5; LPG
Gene Aliases: AD2; APO-E; APOE; LDLCQ5; LPG
UniProt ID: (Human) P02649
Entrez Gene ID: (Human) 348