This antibody is specific for Apolipoprotein E4 and shows no cross-reactivity with ApoE2 or ApoE3.
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
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Protein Aliases: AD2; Apo-E; Apolipoprotein E; apolipoprotein E3; apolipoprotein E4; LDLCQ5; LPG
Gene Aliases: AD2; APO-E; APOE; LDLCQ5; LPG
UniProt ID: (Human) P02649
Entrez Gene ID: (Human) 348